dbSCI: A manually curated database of SARS-CoV-2 inhibitors for COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen of ongoing disease 2019 (COVID-19) global pandemic. Here, by centralizing published cell-based experiments, clinical trials, and virtual drug screening data from NCBI PubMed database, we developed a database SARS-CoV-2 inhibitors for COVID-19, dbSCI, which includes 234 collected publications based on 81 drugs COVID-19 in trials 1305 potential bioinformatics analyses. dbSCI provides four major functions: (1) search target or its inhibitor SARS-CoV-2, (2) browse target/inhibitor information cell screenings, (3) download, (4) submit data. Each entry contains 18 types information, including inhibitor/drug name, targeting protein, mechanism inhibition, experimental technique, sample type, reference information. In summary, relatively comprehensive, credible repository inhibitors/drugs against their mechanisms it will be valuable further studies to control COVID-19.